Efficacy and safety of abemaciclib-based therapy versus tucidinostat-based therapy after progression on palbociclib in patients with HR+HER2− MBC
نویسندگان
چکیده
Background: For patients with hormone receptor-positive HER2-negeative metastatic breast cancer (HR+HER2− MBC), switching to another cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) or targeted drugs different mechanism are considerable treatment strategies post-CDK4/6i. However, no clinical data has been reported on which of the two is more effective. In order explore optimal option post-CDK4/6i, we performed a retrospective comparative cohort study evaluate efficacy and safety abemaciclib-based therapy versus tucidinostat-based after progression palbociclib.
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ژورنال
عنوان ژورنال: Translational breast cancer research
سال: 2023
ISSN: ['2218-6778']
DOI: https://doi.org/10.21037/tbcr-23-9